dglenn: Female (Venus) symbol, with a transistor symbol inside the circle part (TransSister)
[personal profile] dglenn posting in [community profile] transgender
A web search turned up conflicting answers, so I now turn here ... Does spironalactone cause less testosterone to be produced in the body, or does it prevent cells from responding to testosterone that's still there (i.e. bind to testosterone-receptor sites so the testosterone can't)?

Or to put it another way: while I know that spironalactone reduces the effects of testosterone, will a blood test actually show less testosterone present, or will a test show the same or higher amounts of testosterone that's just no longer doing anything?

[xposted by hand to LL]

Date: 2013-03-29 07:24 pm (UTC)
mfb: (TAKA)
From: [personal profile] mfb
(I don't know anything about this unfortunately, but I wanted to say your icon is the cleverest thing and I like it a lot :) )

Date: 2013-09-08 02:20 pm (UTC)
talkswithwind: (medic!)
From: [personal profile] talkswithwind
Holy late post, Batman, but from my understanding Spiro interrupts the metabolic pathway that leads to Testosterone production. That said the wikipedia article says it does both. Also, the citations point to an actual scientific paper (though one from the 70's).

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